40 CSS Layouts to Help with the Basics
By Mitch “Loves Free Things” Keeler
When searching through some of my personal favorite CSS and design resources, I stumbled upon an old favorite of mine - Layout Gala. It might be a ‘bit old, but the advice and layouts here are as good now as they were then.

Via the web site, you can download up to 40 different variations of a basic or skeleton layout. As they state on the site, the main goal of the article was getting the maximum number of layouts based on the same markup, each with valid CSS and HTML, without hacks nor workaround and a good cross-browser compatibility.
Hopefully you will get as much use out of this resource as I have over the years. It comes in great when it comes to fleshing out the basic look and feel of a CSS powered site before getting into all the various design details.
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Original post by Mitch